PEG 20000 was selected as cross-linking agent to prepare cross-linked sodium hyaluronate gel (CHA).Granulated CHA was obtained after a series of technologies:ethanol precipitation,drying,intermittent and instantaneous granulation,screening,redissolving and high-pressure steam sterilization.With the enzyme-resistant degradation rate of gel as index,effects of ethanol amount,drying temperature and drying time on preparation technology were investigated by orthogonal test.The optimum conditions of preparation technology were that the amount of 95% ethanol was 6.5 times of gel,drying the precipitation for 5.0h at 50.0℃。The enzyme-resistant degradation ratio of the granulated CHA was 80.53%,and the sodium hyaluronate(HA)hydrogel was 38.54%.
Reference from Journal of Henan University(Natural Science)
Writer:JIA Ke,ZHAO Yongliang,WANG Weiguo
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singclean | 2017-08-30
2026 Singderm Global Academic Exchange Program First Stop Launches—— China-Thailand Aesthetic Injection Exchange& SymposiumFrom January 22nd to 23rd, Singderm successfully hosted the China-Thailand Aesthetic Injection Exchange& Symposium event, marking a significant step forward in promoting international collaboration within aesthetics. As a key strategic partner of Singderm in the Thai market, Pola Group invited a distinguished delegation of local experts, including: Dr. Rosalyn, Professor, Department of Anatomy, Dhurakij Pundit University, Bangkok Dr. Grace, Technical Director, Doctor Grace Clinic Dr. Jonny, Technical Director, Doctor Jonny Clinic The program was designed to deepen China-Thailand professional dialogue on injectable aesthetics and foster the integration and evolution of Eastern aesthetic concepts and techniques. -
singclean | 2017-08-30
Singclean to Showcase Aesthetic Manufacturing Excellence and Singderm Brand Strength at IMCAS 2026 -
singclean | 2017-08-30
Singclean Medical Strengthens Its Market Position at Russian Health Care Week 2025Singclean Medical successfully concluded its participation in Russian Health Care Week 2025, reinforcing its position as a comprehensive and reliable global supplier in the aesthetic and medical device industry. The exhibition served as a strategic platform for the company to showcase its diversified product portfolio, strong innovation capability, and growing influence in the Russian and neighboring markets.
