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Secrets of The Beauty Industry: The Theory of Hyaluronic Acid Filling Wrinkle Removal
singclean | 2023-05-25


As people age, the amount of hyaluronic acid in the skin decreases and the volume of subcutaneous tissue decreases, resulting in dry and rough skin, wrinkles and fine lines, sunken facial contours, and sagging and sagging skin. At the same time because of social progress and people's pursuit of beauty, the demand for hyaluronic acid dermal injection is gradually increasing, making the industry has been rapid development. In the past few years, many medical beauty institutions and beauty salons have introduced hyaluronic acid dermal injection technology to meet consumers' needs for skin improvement. At the same time, the continuous progress of technology also provides support for the development of the industry, making the hyaluronic acid dermal injection technology more safe, accurate, and more effective.


Injections of hyaluronic acid can replace the lost hyaluronic acid in the skin, increase the moisture content of the skin, and improve skin quality, while improving the elasticity and firmness of the skin, filling in the pits and wrinkles.


Main functions:

(1)Supplement hyaluronic acid: hyaluronic acid has a strong ability to absorb water and moisturize, and can enhance the skin's ability to retain water for a long time. A single molecule of hyaluronic acid can absorb 500 to 1,000 times its body weight in water. By injecting hyaluronic acid, the lost hyaluronic acid in the skin can be replaced and the moisture content of the skin can be increased, thus improving dry skin, dehydration, and fine lines [1].


(2)Increase skin volume: Hyaluronic acids, with their high molecular weight and viscosity, can not only increase volume by physically filling the area in which they are located but also enhance the filling effect by absorbing water. By injecting hyaluronic acid into wrinkles and depressions, it can fill wrinkles, smooth the skin surface, and make the skin look fuller and younger [2].


(3)Stimulating collagen production: hyaluronic acid itself does not directly stimulate collagen production, but the process of injecting hyaluronic acid can trigger a mild inflammatory response, which can stimulate the production of new collagen fibers over time, thereby increasing the elasticity of the skin and improving skin sagging and wrinkles [1].


These properties make hyaluronic acid an ideal filler for wrinkle removal. It can improve skin texture through a moisturizing effect, fill in wrinkles and sunken areas through a volume effect, and has good bio-compatibility, reducing discomfort and risk.


Hyaluronic acid commercially available for injectable and cosmetic purposes is usually derived from microbial fermentation or extracted from animal sources.

Singfiller and Singderm use hyaluronic acid from microbial fermentation, usually with glucose as a carbon source. It is obtained by simple operations such as fermentation in the medium for 48 h and filtration to remove mycelium and impurities using the alcohol precipitation process. Thus ruling out potential allergen problems with animal-derived hyaluronic acid with less risk.


It also has the following advantages:

(1)Immediate effect: After hyaluronic acid injection, you can immediately see the effect of filling and removing wrinkles, making the facial appearance more youthful and energetic.


(2)High safety: hyaluronic acid is a natural substance in the human body, and has good histocompatibility with the human body, almost no allergic reaction. The risk of hyaluronic acid injection is low, and side effects are usually temporary and mild.


(3)Convenient experience: the whole injection time is about half an hour, without a recovery period, and does not affect work and life.


(4)The effect is natural for a long time: generally speaking, the effect can be maintained for about 6 ~ 12 months. The specific maintenance time is affected by the degree of chemical crosslinking of hyaluronic acid, particle size, injection amount, injection site, individual differences, operation techniques, and postoperative care.


As one of the important technologies in the beauty industry, hyaluronic acid dermal injection has broad market prospects and potential. With consumers' pursuit of natural, personalized, and comprehensive beauty solutions, Singclean will continue to develop and innovate in this field.



1. Tracey A. Hotta. The Expanding Market of Health Canada-Approved Hyaluronic Acid-Injectable Dermal Fillers [N]. Plastic Surgical Nursing2017-1-13.

2. Fredric S Brandt & Alex Cazzaniga. Hyaluronic Acid Gel Fillers in the Management of Facial Aging [J]. Clinical Interventions in Aging, 2008, (1): 153.